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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDOA
All Species:
33.94
Human Site:
S336
Identified Species:
57.44
UniProt:
P04075
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04075
NP_000025.1
364
39420
S336
V
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Chimpanzee
Pan troglodytes
A5A6I5
364
39416
S336
V
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Rhesus Macaque
Macaca mulatta
XP_001107644
704
74753
S676
V
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Dog
Lupus familis
XP_849434
364
39485
S336
I
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P05064
364
39337
S336
I
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Rat
Rattus norvegicus
P05065
364
39333
S336
I
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508559
364
39349
G336
V
K
R
A
E
V
N
G
L
A
A
Q
G
K
Y
Chicken
Gallus gallus
P07341
364
39277
S336
C
K
R
A
Q
I
N
S
L
A
C
R
G
Q
Y
Frog
Xenopus laevis
NP_001079799
364
39387
S336
V
K
R
A
L
A
N
S
L
A
C
Q
G
K
Y
Zebra Danio
Brachydanio rerio
Q8JH70
363
39241
G336
I
K
R
A
E
A
N
G
L
A
A
Q
G
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07764
361
39029
A333
E
L
L
K
R
A
K
A
N
G
D
A
A
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P54216
366
39222
S338
L
H
R
A
Q
V
N
S
L
A
S
V
G
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P08440
355
38586
K327
A
A
F
L
A
R
C
K
A
N
S
E
A
T
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P22197
358
38792
K330
L
T
R
C
K
A
N
K
D
A
T
L
G
K
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.5
98.6
N.A.
97.8
96.9
N.A.
82.9
71.9
88.1
81.5
N.A.
70.8
N.A.
65.8
N.A.
Protein Similarity:
100
99.4
51.5
99.4
N.A.
99.7
99.4
N.A.
89.8
83.2
92.5
87.6
N.A.
81.3
N.A.
76.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
73.3
66.6
100
73.3
N.A.
6.6
N.A.
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
80
100
80
N.A.
20
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
59.6
N.A.
58.5
N.A.
N.A.
Protein Similarity:
N.A.
69.7
N.A.
69.7
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
79
8
72
0
8
8
86
15
8
15
0
0
% A
% Cys:
8
0
0
8
0
0
8
0
0
0
58
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
8
0
0
0
15
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
0
8
0
0
86
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
29
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
72
0
8
8
0
8
15
0
0
0
0
0
79
0
% K
% Leu:
15
8
8
8
50
0
0
0
79
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
86
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
0
0
0
0
0
0
65
0
15
0
% Q
% Arg:
0
0
86
0
8
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
65
0
0
15
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% T
% Val:
36
0
0
0
0
15
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _